Paras Health in Gurugram has successfully performed the world’s first living donor liver transplant in combination with a double heart valve surgery.
The rare and highly complex procedure was carried out on a 55-year-old woman from Kyrgyzstan, Anara M, who was suffering from end-stage autoimmune liver disease along with serious damage to both her mitral and tricuspid heart valves. According to the hospital, she had undergone several hospitalizations over the years before arriving at Paras Health Gurugram on February 25, 2025, seeking advanced treatment for her rapidly declining health.
A detailed pre-surgical evaluation revealed that she urgently needed a liver transplant as well as surgical repair of the two heart valves-making it an exceptionally challenging case.
The surgery was performed by a multidisciplinary team led by Dr. Vaibhaw Kumar, Director, Institute of Liver Transplant & GI Surgery, along with Dr. Amit Rastogi, Chairman of the same institute, and Dr. Sanjay Kumar, Vice Chairman, Cardiac Surgery. They were supported by Dr. Rajnish Monga, Chairman, Gastroenterology & Hepatology, and Dr. Amit Bhushan Sharma, Director & Unit Head, Cardiology, among many other specialists.
“This is the first time anywhere in the world that a living donor liver transplant has been performed alongside simultaneous repair of both mitral and tricuspid valves,” said Dr. Vaibhaw Kumar. “Combining these two procedures raised the level of risk and complexity dramatically, but our team executed it with precision, coordination, and deep expertise.”
Dr. Sanjay Kumar added,
“The patient’s heart condition made the case extremely high-risk. Without repairing the mitral and tricuspid valves first, a liver transplant would not have been viable. Performing both surgeries together in one sitting demanded exceptional teamwork and advanced infrastructure, but it ultimately gave our patient a new lease on life.”
The milestone operation was conducted on March 26, 2025. The team first carried out a 4‑hour cardiac surgery to repair the valves. After the heart procedure, the patient was briefly awakened in the operating room to ensure stable heart function before moving ahead. This was followed by a 12‑hour living donor liver transplant, taking the total surgical time to about 16 hours. Around 18–20 specialists-including surgeons, anesthetists, nurses, and technicians-worked together to make the surgery a success.
The liver donor was the patient’s 23‑year‑old nephew. He recovered well, was discharged five days after surgery, and returned to Kyrgyzstan within three weeks, resuming normal activities soon after.
Anara’s post‑operative course was smooth: eight days in intensive care, seven days in a regular room, and discharge on the 15th day. Six weeks later she returned home, and three months on, she has regained full health and a normal lifestyle.
Paras Health credits this success to its state‑of‑the‑art facilities, including hybrid operating theaters, AI‑assisted surgical planning, real‑time 3D imaging, and a dedicated transplant ICU. The hospital plans to publish this case in a leading international medical journal to guide other centers managing similarly complex multi‑organ transplant cases.
This landmark achievement once again underscores India’s growing leadership in cutting‑edge medical innovation.
Source: ET Healthworld