Researchers at IIT Guwahati have developed a novel, low-cost method to detect and measure SARS-CoV-2 using sedimentation of a clay-virus-electrolyte mixture. This approach, using Bentonite clay, offers a simpler and more affordable alternative to complex methods like PCR and less accurate antigen or antibody tests.
The study, published in Applied Clay Science, was led by Prof. T V Bharat (Civil Engineering) and Prof. Sachin Kumar (Biosciences), with researchers Dr. Himanshu Yadav and Deepa Mehta. They found that the virus binds effectively to negatively charged clay particles at room temperature and neutral pH, allowing detection by observing sedimentation speed.
Validated against standard detection methods like plaque assays and RT-PCR, the technique showed promising accuracy. It can also be extended to detect other viruses, such as NDV, relevant to poultry farming.
This method holds significant potential for virus detection in resource-limited areas and during pandemics. The team now plans clinical trials in partnership with medical and industry collaborators to further develop the technique for broader public health use.